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Emotional stress and the development of multiple sclerosis: case-control evidence of a relationship

S Warren, S Greenhill, K G Warren

    Journal of Chronic Diseases
    |January 1, 1982
    PubMed

    One hundred multiple sclerosis (MS) patients were compared to hospital controls, for life stress prior to onset age in the MS patients and controls did not differ on: the happiness of their childhood environment; their pre-onset age reaction to life's problems (relaxed and taking things in stride/tense or easily upset); or on their tendency to seek professional help with an emotional problem. However significantly more MS patients than controls reported that they were under unusual stress in the 2 yr period prior to onset age; and the MS patients described a greater number of stressful life situations, or single events, than the controls.

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