Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Asymptomatic Bartter's syndrome

G L Barbour, J O Day

    Southern Medical Journal
    |November 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Bartter syndrome, a cause of hypokalemia, involves renal wasting of electrolytes. This case highlights unexplained hypokalemia as a potential indicator of undiagnosed Bartter syndrome.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hyperglycaemia-related complications at the time of diagnosis can cause permanent neurological disability in children with neonatal diabetes.

    Diabetic medicine : a journal of the British Diabetic Association·2017
    Same author

    Quality improvement in the US Veterans Health Administration.

    International journal for quality in health care : journal of the International Society for Quality in Health Care·1997
    Same author

    Contribution of locally and externally designed quality management activities to hospitals' efforts to improve patient care.

    The Western journal of medicine·1997
    Same author

    Development of a quality improvement checklist for the Department of Veterans Affairs.

    The Joint Commission journal on quality improvement·1994
    Same author

    Usefulness of a discharge diagnosis of sepsis in detecting iatrogenic infection and quality of care problems.

    American journal of medical quality : the official journal of the American College of Medical Quality·1993
    Same author

    Studies of the permeability of isolated porcine peritoneum to nutrients: saccharides.

    Biochemical medicine and metabolic biology·1991
    Same journal

    SMA's 6th Annual Physicians-in-Training Leadership Conference Abstract Presentations.

    Southern medical journal·2026
    Same journal

    Potential Impact of Lower Federal Loan Availability on Medical Education in Appalachia.

    Southern medical journal·2026
    Same journal

    Experiential Mentorship Skills Training: The Effect on Real-Life Mentoring.

    Southern medical journal·2026
    Same journal

    Social Pressure: How Early Social Context Shapes Career Interest in Medicine.

    Southern medical journal·2026
    Same journal

    Comparing Speed and Accuracy of Artificial Intelligence Large Language Models on the Orthopedic In-Training Examination.

    Southern medical journal·2026
    Same journal

    Don't Wait to Talk about Weight: A 2-Hour Interactive Curriculum Improves Medical Student Skills with Weight Management.

    Southern medical journal·2026
    See all related articles

    Area of Science:

    • Nephrology
    • Endocrinology
    • Internal Medicine

    Background:

    • Bartter syndrome is a rare genetic disorder characterized by renal salt wasting.
    • It leads to electrolyte imbalances, including hypokalemia, metabolic alkalosis, and hyperreninemia.

    Observation:

    • A 63-year-old man presented with asymptomatic hypokalemia.
    • Investigations revealed elevated plasma renin and aldosterone, angiotensin resistance, and increased urinary prostaglandin excretion.
    • Tubular studies indicated a proximal tubule sodium reabsorption defect with renal potassium and magnesium wasting.

    Findings:

    • Indomethacin reduced prostaglandin excretion and hormone levels but did not resolve hypokalemia.
    • Spironolactone normalized serum potassium but not magnesium levels.

    Related Experiment Videos

  • This suggests complex electrolyte disturbances in Bartter syndrome.

    • Implications:

    • Bartter syndrome can present asymptomatically and should be considered in unexplained hypokalemia.
    • Renal wasting of sodium, potassium, and magnesium are key features.
    • Management requires addressing hormonal and tubular defects.