Ocular involvement in lupus erythematosus profundus (panniculitis)

Lupus erythematosus profundus (panniculitis) is a rare clinical variant of lupus erythematosus. It has not been implicated previously as a cause of lid edema or proptosis. In this report, three patients who had eyelid edema as the initial manifestation of lupus erythematosus profundus are presented. The ocular manifestations improved with antimalarial therapy.