Related Experiment Video
Updated: Aug 13, 2026

Microwave-driven Synthesis of Iron Oxide Nanoparticles for Fast Detection of Atherosclerosis
Published on: March 22, 2016
[Sodium azide--an activator of serum lipoproteins peroxidation]
Abstract:
Addition of even small amounts of sodium azide to preparations of blood serum lipoproteins of various classes, isolated by ultracentrifugation, intensified peroxidation of their lipids. At the same time, physical structure of blood serum lipoproteins was impaired as shown by activation of chemoluminescence using fluorescent probes pyrene and I-aniline naphthalene-8-sulphonate simultaneously with an increase in content of malonic dialdehyde. The data obtained suggest that the results of studies of protein-lipid structures in media containing azides have to be interpreted very carefully to avoid unwarranted conclusions.
More Related Videos
07:29Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
11:13Enrichment of Native Lipoprotein Particles with microRNA and Subsequent Determination of Their Absolute/Relative microRNA Content and Their Cellular Transfer Rate
Published on: May 9, 2019
Related Concept Videos
Preparation of 1° Amines: Azide Synthesis
Azide ions act as good nucleophiles and react with unhindered alkyl halides to form alkyl azides. Alkyl azides do not participate in further nucleophilic substitution reactions, thereby eliminating the chances of polyalkylated products. Alkyl azides are reduced by hydride-based reducing agents, like lithium aluminum...
Diazonium Group Substitution: –OH and –H
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism
Radical Autoxidation
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Bioactivation and Tissue Toxicity