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Updated: Oct 23, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
[Physico-chemical properties of the blood of patients with chronic kidney failure]
Abstract:
Physico-chemical characteristics of blood from patients with chronic kidney insufficiency were studied by means of ionization equilibrium in whole blood, blood plasma and erythrocytes suspended in physiological solution. The curves of ionization equilibrium were registered by changes of pH under conditions of controlled heating (58 degrees) of blood, blood plasma and erythrocytes. Electric charge of proteins in blood plasma, erythrocytes and, especially, in whole blood was decreased in patients with chronic kidney insufficiency as compared with healthy persons. In the patients with kidney impairment, as distinct from healthy persons increase in ion strength improved the blood physico-chemical properties and an artificial elevation of hematocrit decreased the electric charge of blood and deteriorated the immunological properties of blood plasma proteins.
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