[Prenatal AB0(H) blood group determination of amniotic fluid cells by mixed cell agglutination]

A modification of the mixed-cell agglutination reaction (MCAR) was used in prenatal AB0(H) blood typing of cells obtained from 41 samples of amniotic fluid. The findings are compared with results obtained from the use of the agglutination inhibition test in testing water-soluble AB0(H) substances of amniotic fluid based on the same samples. For prenatal AB0(H) typing, MCAR exhibited advantages over the agglutination inhibition test. Completion of data in this field will provide a good foundation for prenatal detection and identification of hereditary factors which can be linked with gene loci of the AB0 system.