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Published on: April 25, 2016
Effect of orally administered hydrocortisone on the rate of aqueous flow in man
Abstract:
We studied the possible influence on the rate of aqueous flow of peroral hydrocortisone in 8 normal eyes of 8 normal subjects by means of fluorophotometry. In the control period, the mean value of ko obtained was 0.011 +/- 0.0023 min, where ko was the loss coefficient from the anterior chamber. On another day (hydrocortisone trial period), fluorophotometry was again performed after giving a dose of oral hydrocortisone (80 mg) and the mean value of ko obtained was 0.020 +/- 0.0027/min. The mean difference in ko values between the control period and the hydrocortisone trial period was significant (P less than 0.001). An increased rate of aqueous flow after giving a dose of oral hydrocortisone was demonstrated.
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