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Aluminum absorption in the rat everted gut sac
Abstract:
Intestinal absorption of aluminum was studied in rat everted gut sacs. Aluminum transport and aluminum uptake in the jejunum initially rose with increasing bath aluminum concentration, but reached a plateau with high bath aluminum concentrations. The aluminum transport was inhibited by dinitrophenol, absence of glucose, and a temperature of 4 degrees C. There was no change with acute renal failure, chronic renal failure, parathyroidectomy, or parathyroid hormone injection. The aluminum absorption from the rat jejunum appears to involve an energy-dependent, carrier-mediated mechanism.