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An automatic method for Thrombotest on the 'Cobas Bio' centrifugal analyser
Scandinavian Journal of Clinical and Laboratory Investigation
|December 1, 1982
Summary
The Thrombotest assay was successfully adapted to the Cobas Bio centrifugal analyser, showing excellent correlation with existing methods. This automation significantly reduces manual labor and processing time for large-scale testing.
Area of Science:
- Clinical Chemistry
- Hematology
- Laboratory Automation
Background:
- The Thrombotest assay is a standard method for evaluating blood coagulation.
- Manual performance of coagulation assays can be time-consuming and labor-intensive.
- Advancements in laboratory automation offer potential for improved efficiency.
Purpose of the Study:
- To adapt the Thrombotest assay for use on the Cobas Bio centrifugal analyser.
- To evaluate the performance and correlation of the adapted assay.
- To assess the potential for time and labor savings.
Main Methods:
- Adaptation of the Thrombotest assay protocol for the Cobas Bio centrifugal analyser.
- Comparative analysis of results obtained from the centrifugal analyser and a traditional coagulometer.
- Assessment of time and manual labor requirements.
Main Results:
- Excellent correlation (r = 0.9972) was observed between the Thrombotest assay results on the Cobas Bio analyser and a coagulometer.
- The automated method demonstrated a significant reduction in manual labor and time.
- Approximately 50% efficiency gain was estimated for large series testing.
Conclusions:
- The Cobas Bio centrifugal analyser provides a reliable and accurate platform for the Thrombotest assay.
- Automation of the Thrombotest assay significantly enhances laboratory efficiency.
- This adaptation is particularly beneficial for high-volume testing environments.