Related Experiment Videos
[Value of determining trace elements in septicemia. Clinical correlations, prognostic value]
Anesthesie, Analgesie, Reanimation
|May 1, 1978
Summary
Septicemia causes a decrease in serum trace elements. Survivors show rapid recovery of these elements, while non-survivors do not, highlighting phosphorus levels and suggesting a role for S.R.E. activity.
Area of Science:
- Biochemistry
- Clinical Medicine
- Trace Element Metabolism
Context:
- Sepsis is a life-threatening condition characterized by a dysregulated host response to infection.
- Serum oligo-element levels are altered during septic episodes.
- Understanding these alterations is crucial for predicting patient outcomes.
Purpose:
- To investigate the changes in serum oligo-elements in patients with septicemia.
- To analyze the longitudinal trends of these elements in survivors versus non-survivors.
- To explore the potential role of S.R.E. activity in these metabolic perturbations.
Summary:
- A statistically significant decrease in serum oligo-elements was observed in 17 septicemic patients.
- Longitudinal analysis revealed rapid correction of these perturbations in survivors, but not in non-survivors.
- Phosphorus levels showed particularly interesting trends, with S.R.E. activity implicated in the physiopathology.
Impact:
- Provides insights into the metabolic disturbances associated with sepsis.
- Suggests potential biomarkers for prognosis in septic patients.
- Highlights the importance of trace element monitoring and management in sepsis.