[Morphological characteristics of Peyronie's disease]

Morphological examinations of 40 operation preparations in Peyronie's disease were done by light and electron microscopy. The studies showed the main changes in this disease to localize in tunica albuginea which thickens considerably forming a plaque. The latter presents bundles of thickened collagen fibers with altered fibroblasts and perivascular round-cell infiltrates. Sometimes areas of formation of cartilage and bone tissue were found. The combination of Peyronie's disease with Dupuytren's contracture was confirmed.