Pilar sheath acanthoma

Area of Science:

• Dermatopathology
• Oncology
• Dermatology

Background:

• Benign follicular tumors are a diverse group of skin neoplasms.
• Accurate diagnosis is crucial for appropriate patient management.
• Pilar sheath acanthoma is a newly recognized entity.

Purpose of the Study:

• To describe the clinical and histological features of a newly recognized benign follicular tumor.
• To establish the distinct characteristics of pilar sheath acanthoma.
• To aid in differentiating it from other follicular neoplasms.

Main Methods:

• Case series of nine patients.
• Clinical description of lesions (location, appearance, duration).
• Histopathological examination of tumor architecture and cellular components.

Main Results:

• Nine cases of pilar sheath acanthoma observed in patients aged 46-75.
• Lesions were solitary, asymptomatic, skin-colored nodules with a central keratin plug.
• Histology revealed a central cystic cavity with epidermoid keratinization and hair sheath epithelium lobules.

Conclusions:

• Pilar sheath acanthoma is a distinct benign follicular neoplasm.
• It presents with characteristic clinical and histological findings.
• Differential diagnosis should include trichofolliculoma and dilated pore.