Larva migrans complicated by Loeffler's syndrome

Area of Science:

• Parasitology
• Tropical Medicine
• Dermatology

Background:

• Larva migrans is a helminthic infection caused by larval forms of hookworms.
• Cutaneous larva migrans (CLM) is acquired through skin contact with parasite-infested soil or sand.

Observation:

• A married couple vacationing on the Gulf of Mexico developed CLM.
• Both patients subsequently presented with migratory pulmonary infiltrates and peripheral eosinophilia, indicative of Loeffler's syndrome.

Findings:

• Cutaneous lesions of CLM were treated effectively with topical thiabendazole, resolving within two weeks.
• The associated Loeffler's syndrome, a pulmonary manifestation, resolved with symptomatic management over eight weeks.

Implications:

• This case highlights the potential for systemic complications, such as Loeffler's syndrome, following cutaneous larva migrans.
• Prompt diagnosis and treatment of CLM are crucial to prevent or manage pulmonary involvement.
• Topical thiabendazole is an effective treatment for cutaneous larva migrans.