Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasma noradrenaline concentrations during isometric exercise

R J Vecht, G W Graham, P S Sever

    British Heart Journal
    |November 1, 1978
    PubMed
    Summary

    Isometric exercise significantly increases plasma noradrenaline levels. This rise may pose risks for patients with heart conditions, particularly those with impaired left ventricular function, due to increased susceptibility to arrhythmias.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tissue Doppler echocardiography predicts long-term cardiovascular mortality: the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) legacy 20-year follow-up study.

    Open heart·2025
    Same author

    Some comments on male circumcision.

    The Israel Medical Association journal : IMAJ·2013
    Same author

    ASCORE: an up-to-date cardiovascular risk score for hypertensive patients reflecting contemporary clinical practice developed using the (ASCOT-BPLA) trial data.

    Journal of human hypertension·2013
    Same author

    Metabolic syndrome, impaired fasting glucose and obesity, as predictors of incident diabetes in 14 120 hypertensive patients of ASCOT-BPLA: comparison of their relative predictability using a novel approach.

    Diabetic medicine : a journal of the British Diabetic Association·2011
    Same author

    How common is true resistant hypertension?

    Journal of human hypertension·2010
    Same author

    The economic consequences of non-adherence to lipid-lowering therapy: results from the Anglo-Scandinavian-Cardiac Outcomes Trial.

    International journal of clinical practice·2010

    Area of Science:

    • Cardiology
    • Neuroendocrinology

    Background:

    • Noradrenaline is a key stress hormone.
    • Understanding its response to exercise is crucial for cardiovascular health assessment.

    Purpose of the Study:

    • To investigate plasma noradrenaline changes during isometric stress.
    • To compare noradrenaline levels in the left ventricle and pulmonary artery.

    Main Methods:

    • Blood samples collected from 12 patients during cardiac catheterization.
    • Analysis of noradrenaline concentrations at rest, during, and after isometric hand grip exercise.

    Main Results:

    • Isometric exercise caused a significant increase in plasma noradrenaline.
    • No significant difference in noradrenaline levels between left ventricle and pulmonary artery samples.
    • Patients with left ventricular dysfunction showed higher noradrenaline levels.

    Conclusions:

    • Moderate isometric exercise elevates noradrenaline, potentially increasing arrhythmia risk in susceptible individuals.
    • This highlights the importance of exercise stress testing considerations for patients with cardiovascular disease.

    Related Experiment Videos