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Experimental infection of neonatal striped skunks (Mephitis mephitis) with infectious bovine rhinotracheitis virus

Insights

Infectious bovine rhinotracheitis virus (IBRV) caused fatal systemic infections in skunks. This research confirms IBRV as a cause of disease and lesions in neonatal skunks.

Area of Science:

  • Veterinary Virology
  • Pathology
  • Wildlife Disease

Background:

  • Infectious bovine rhinotracheitis virus (IBRV) is a significant pathogen in cattle.
  • The susceptibility of wildlife species, such as skunks (Mephitis mephitis), to IBRV is not well-documented.

Purpose of the Study:

  • To investigate the effects of experimental IBRV infection in neonatal skunks.
  • To determine if IBRV can cause systemic disease and characteristic lesions in this species.

Main Methods:

  • Neonatal skunks were experimentally infected with IBRV.
  • Virus isolation and immunofluorescence assays were performed on tissue samples.
  • Histopathological examination of affected organs was conducted.

Main Results:

  • Experimental IBRV infection resulted in fatal systemic disease in neonatal skunks.
  • Virus isolation and immunofluorescence confirmed the presence of IBRV in association with observed lesions.
  • Histopathology revealed multifocal necrosis in the liver and adrenal glands.

Conclusions:

  • Neonatal skunks are highly susceptible to IBRV, developing fatal systemic infections.
  • IBRV can induce significant pathological changes, including hepatic and adrenal necrosis, in skunks.
  • This study highlights the potential for IBRV to impact wildlife populations.

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