[Submicroscopic changes in the thyroid gland in burns]

Submicroscopic changes of thyrocytes and perifollicular capillarites were studied in pubertal guinea pig males on the 1st, 2nd, 7th, 14th, 21st, and 28th days of burn disease. During the burn shock macrofollicles formed by flattened thyrocytes dominated in the thyroid gland. The capillaries were characterized by the lumen dilatation and disturbance of the wall ultrastructure. The cells increased in height, and there was hypertrophy and hyperplasia of the intracellular organellae on the 7th and the 14th days. Along with hyperplastic processes in thyrocytes and endothelial cells destruction of the membrane cell components developed which caused deep necroblas cell injury and severe disturbances of the vascular parenchymatous relationships in the organ at later periods of the disease (the 21st and 28th days).