[Effect of haloperidol on fenamin stereotypy]

Bilateral electrolytic lesion of the striatum disturbs the ability of haloperidol (0.1 mg/kg) to normalize the avoidance behaviour of rats given amphetamine (5 mg/kg). Low doses of the neuroleptic (0.03--0.06 mg/kg) potentiate the inhibition of amphetamine-induced stereotypy that occurs after discontinuation of repeated electric stimulation of the cat caudate nucleus. Participation of the striate mechanisms in the realization of specific psychotropic acitivity of neuroleptics is suggested.