Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sleep and temporal lobe epilepsy: a case study with depth electrodes

J Montplaisir, M Laverdière, J M Saint-Hilaire

    Neurology
    |October 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Differential effects of sleep deprivation on sleepwalking: Role of demographic and clinical profiles.

    Sleep medicine·2024
    Same author

    Occupational pesticide exposure, cancer and chronic neurological disorders: A systematic review of epidemiological studies in greenspace workers.

    Environmental research·2021
    Same author

    Pesticides Exposure by Air in Vineyard Rural Area and Respiratory Health in Children: A pilot study.

    Environmental research·2018
    Same author

    Maternal occupational exposures to nanoscale particles and small for gestational age outcome in the French Longitudinal Study of Children.

    Environment international·2018
    Same author

    Maternal cumulative exposure to extremely low frequency electromagnetic fields and pregnancy outcomes in the Elfe cohort.

    Environment international·2017
    Same author

    Presynaptic NMDA receptors: Roles and rules.

    Neuroscience·2015
    Same journal

    Phenotype, Severity, and Therapy of Patients With LRP4 Antibody-Associated Myasthenia Gravis in the German Myasthenia Gravis Registry.

    Neurology·2026
    Same journal

    Association of Changes in Intrinsic Capacity With Cognitive Decline and Dementia: A Prospective Cohort Study.

    Neurology·2026
    Same journal

    Role of the Upper Motor Neuron in the Generation of Fasciculations in Early Disease Stages of Amyotrophic Lateral Sclerosis.

    Neurology·2026
    Same journal

    Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

    Neurology·2026
    Same journal

    Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

    Neurology·2026
    Same journal

    Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

    Neurology·2026
    See all related articles

    This study on hippocampal epilepsy found seizures were shorter during sleep but awakening, particularly from REM sleep, triggered generalized seizures. Night terrors were linked to seizures, resolving after surgery.

    Area of Science:

    • Neurology
    • Epileptology
    • Sleep Medicine

    Background:

    • Investigating the relationship between sleep states and seizure activity in patients with epilepsy.
    • Understanding the specific characteristics of hippocampal epilepsy and its nocturnal manifestations.

    Observation:

    • A patient with right hippocampal epilepsy experienced frequent nocturnal and diurnal seizures.
    • Depth electrode recordings revealed shorter focal seizure discharges in the right hippocampus during REM and non-REM sleep.
    • Awakening, especially from or shortly after REM sleep, was observed to facilitate generalized seizures.

    Findings:

    • Seizure discharges in the right hippocampus were shorter during sleep (REM and non-REM).
    • Generalized seizures were more likely to occur upon awakening, particularly after REM sleep.

    Related Experiment Videos

  • No ultradian fluctuations in seizure frequency or duration were noted during diurnal recordings.
  • Night terrors, but not nightmares, resolved post-right temporal lobectomy, suggesting they were an ictal manifestation.

    • Implications:

    • Sleep state, particularly REM sleep, plays a critical role in seizure precipitation in some epilepsy types.
    • Awakening from sleep can act as a trigger for generalized seizures in individuals with hippocampal epilepsy.
    • Night terrors may represent a form of ictal manifestation in certain epilepsy patients.
    • Surgical intervention, such as temporal lobectomy, can alleviate seizure-related phenomena like night terrors.