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Acquired methemoglobinemia

M E Geffner, D R Powars, W T Choctaw

The Western Journal of Medicine

|January 1, 1981

Summary

This summary is machine-generated.

Acquired methemoglobinemia is increasingly seen, often linked to silver nitrate burn treatments. Prompt discontinuation of the agent and methylene blue therapy are crucial for recovery.

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Area of Science:

Clinical Toxicology
Pediatrics
Dermatology

Background:

Acquired methemoglobinemia cases are rising in Los Angeles.
This condition affects both infants and adults.

Purpose of the Study:

To identify common causes of acquired methemoglobinemia.
To highlight the role of silver nitrate in burn wound care.

Main Methods:

Retrospective review of 18 patients with acquired methemoglobinemia.
Analysis of causative agents, including topical agents, diet, and medications.

Main Results:

Silver nitrate for burn prophylaxis was the most frequent cause.
Other causes included nitrate-rich vegetables, food additives, and drug overdoses.

One pediatric case resulted in fatal septicemia with hypoxia.

Conclusions:

Silver nitrate use in burn patients requires vigilant methemoglobin monitoring.
Early intervention with methylene blue is effective for methemoglobinemia treatment.