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Related Experiment Videos

Indocyanine green fluorescence angiography

L Hyvärinen, R W Flower

    Acta Ophthalmologica
    |August 1, 1980
    PubMed
    Summary

    Refined indocyanine green (ICG) fluorescence angiography enhances imaging of choroidal circulation. Improved camera optics and lighting allow for higher resolution and faster frame rates, aiding laboratory investigations.

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    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Physiology

    Background:

    • Indocyanine green (ICG) fluorescence angiography is a valuable tool for studying ocular circulation.
    • Existing methods have limitations in resolution and speed for dynamic choroidal vascular studies.

    Purpose of the Study:

    • To present technical refinements to indocyanine green (ICG) fluorescence angiography for improved visualization of choroidal circulation.
    • To evaluate the efficacy of these modifications in laboratory and clinical settings.

    Main Methods:

    • Modified Zeiss fundus camera with anti-reflection coated lenses for enhanced light transmission around 800 nm.
    • Utilized a 300-watt indium iodide continuous light source, replacing xenon flash lamps.
    • Achieved spatial resolution of 7.4 microns and imaging at 20 frames per second.

    Main Results:

    • Increased light transmission and improved spatial resolution enhance image quality.
    • Higher frame rates allow for detailed documentation of rapid blood flow in the choroid.
    • Retinal exposure time is limited to 11.9 seconds, adequate for capturing choroidal dye passage.

    Conclusions:

    • Technical advancements in ICG angiography offer superior imaging of choroidal vasculature.
    • This refined technique has the potential to alter current interpretations of choroidal circulatory phenomena.
    • ICG angiography is an effective tool for experimental investigations of the choroid.

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