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Related Experiment Videos

Blue fingertips associated with myxedema

C P Crotty, C H Dicken

    Archives of Dermatology
    |March 1, 1981
    PubMed
    Summary

    Blue telangiectases on fingertips, linked to myxedema, resolved with thyroid treatment. This suggests mucin deposition around small blood vessels caused the vascular occlusion symptoms.

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    Area of Science:

    • Dermatology
    • Endocrinology
    • Vascular Medicine

    Background:

    • Myxedema, a condition associated with hypothyroidism, can manifest with various cutaneous and vascular changes.
    • Peripheral vascular occlusion symptoms, such as abnormal Doppler findings, are typically linked to circulatory system disorders.

    Observation:

    • A 42-year-old woman presented with blue telangiectases on her fingertips.
    • These telangiectases were observed in conjunction with clinical signs of myxedema.
    • Doppler ultrasound revealed abnormalities consistent with peripheral vascular occlusion.

    Findings:

    • Thyroid replacement therapy led to the complete resolution of fingertip telangiectases.
    • Significant improvement in Doppler ultrasound findings was observed following thyroid hormone normalization.
    • The clinical presentation is hypothesized to result from mucin deposition around digital blood vessels.

    Implications:

    • This case highlights a potential, previously unrecognized, cutaneous manifestation of myxedema.
    • It underscores the importance of considering thyroid dysfunction in patients presenting with unusual vascular findings.
    • Effective management of hypothyroidism can reverse these specific vascular and dermatological symptoms.

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