Biochemical and hematological evaluation of chloroprene workers

Swedish and Russian investigators have reported a variety of biochemical and hematological alterations in choloroprene-exposed workers. In view of their findings, an evaluation of the biochemical and hematological status of active chloroprene workers at a Du Pont Company plant was undertaken. The distributions of biochemical and hematological values of 336 currently exposed and 227 previously exposed chloroprene workers were compared to those of 283 workers never exposed to chloroprene. The comparative analysis did no indicate or suggest that chloroprene workers have biochemical or hematological alterations, or both, of medical significance. Some of the biochemical and hematological alterations cited by other researchers were investigated in the current study. Of those alterations investigated, none were found among the current cohort of chloroprene-exposed workers.