[Ascorbic acid content in the blood serum and lymphoid organs in antigenic exposure]
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Updated: Oct 20, 2026

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
Published on: April 11, 2014
Abstract:
Seven and 14 days following immunization with sheep red blood cells, the guinea-pigs incapable of synthesizing ascorbic acid showed its pronounced decrease in blood serum accompanied by elevation of ascorbate content in the thymus and spleen, central organs responsible for immunogenesis. Immunization of rats capable of synthesizing ascorbic acid did not lead to its changes in the blood serum, thymus or spleen.
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