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[Vitamin E: immunocorrecting effect in bronchial asthma patients]
Voprosy Meditsinskoi Khimii
|July 1, 1995
Summary
Vitamin E supplementation in bronchial asthma patients boosts T and B lymphocyte levels and enhances granulocyte activity. This immunological effect also reduces serum lysozyme and complement activity.
Area of Science:
- Immunology
- Pulmonology
- Nutritional Science
Context:
- Bronchial asthma is a chronic respiratory condition characterized by airway inflammation.
- Multimodality therapy is the standard approach for managing asthma.
- The role of micronutrients like Vitamin E in modulating the immune response in asthma is under investigation.
Purpose:
- To investigate the immunological effects of Vitamin E supplementation in patients with bronchial asthma receiving multimodality therapy.
Summary:
- Vitamin E supplementation in bronchial asthma patients led to increased peripheral blood levels of T lymphocytes, with enhanced functional activity.
- The study observed an increase in B cell levels, characterized by a higher count of mature B lymphocytes and a decrease in immature B cells.
- Vitamin E was found to enhance the phagocytic activity of peripheral granulocytes, while serum lysozyme and complement activity declined.
Impact:
- These findings suggest Vitamin E may play a beneficial role in modulating the immune system of asthma patients.
- Further research could explore Vitamin E as an adjunct therapy to improve immunological parameters in bronchial asthma.
- Understanding these immunological changes could lead to novel therapeutic strategies for asthma management.