Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experience with 130 polytetrafluoroethylene grafts

J G Sladen, T M Maxwell

    American Journal of Surgery
    |May 1, 1981
    PubMed
    Summary

    Polytetrafluoroethylene (Gore-Tex) grafts show disappointing results in below-knee and femorotibial bypass surgery. While versatile, neointimal hyperplasia and occlusion limit their effectiveness compared to vein grafts.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Patency of superficial femoral vein employed as a crossover femoral artery bypass conduit.

    Annals of vascular surgery·2002
    Same author

    A common deletion at chromosomal region 17q21 in sporadic prostate tumors distal to BRCA1.

    Genomics·2001
    Same author

    Chromosomal clues to the development of prostate tumors.

    The Prostate·1999
    Same author

    Chromosome 7 abnormalities in prostate cancer detected by dual-color fluorescence in situ hybridization.

    Cancer genetics and cytogenetics·1998
    Same author

    An aggressive local approach to vascular graft infection.

    American journal of surgery·1998
    Same author

    Prosthetic-vein composite graft with remote popliteal arteriovenous fistula.

    American journal of surgery·1996

    Area of Science:

    • Vascular Surgery
    • Biomaterials Science

    Background:

    • Polytetrafluoroethylene (PTFE) grafts are utilized in vascular reconstructions.
    • Assessing long-term outcomes of PTFE grafts in specific arterial locations is crucial.

    Purpose of the Study:

    • To evaluate the efficacy and complications of polytetrafluoroethylene (Gore-Tex) grafts in femoropopliteal and femorotibial bypass procedures.
    • To identify limitations and potential improvements for PTFE graft utilization.

    Main Methods:

    • Analysis of 130 operations using polytetrafluoroethylene grafts.
    • Follow-up duration of 1 to 3 years.
    • Assessment of graft patency, complications, and specific failure modes.

    Main Results:

    • Disappointing outcomes observed for below-knee femoropopliteal and femorotibial PTFE grafts.
    • Graft versatility noted, including crossing the knee joint and maintaining patency in poor outflow.
    • Neointimal hyperplasia identified as a primary disadvantage, particularly in small vessels, leading to occlusion.

    Conclusions:

    • Polytetrafluoroethylene grafts remain a second-choice option compared to vein grafts for below-knee and femorotibial reconstructions.
    • Further investigation into composite grafts combining PTFE with vein for small vessel applications is warranted.

    Related Experiment Videos