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Immunization with purified myelin-associated glycoprotein does not evoke myelination-inhibiting or demyelinating
Brain Research
|March 30, 1981
Abstract:
Antisera produced in rabbits against purified myelin-associated glycoprotein did not inhibit myelin formation in cerebellar tissue cultures or demyelinate centrally or peripherally myelinated fibers in spinal cord-dorsal root ganglia cultures. These results suggest that antibodies directed against other myelin components are responsible for the myelination-inhibition and demyelination produced by anti-central nervous system (CNS) and anti-myelin antisera in vitro.