[Autoradiographic study of the action of yohimbine on rat spermatogenesis]

The authors found an increase in the number of labelled spermatogonia and spermatocytes with 35 to 40% in the experimental animals as a result of performed quantitative studies on mature male rats after chronic treatment with jochimbin and simultaneous application of 3H-thymidine. This statistically significant difference in comparison with the control animals showed that jochimbin stimulated the mitotic activity of spermatogonia as a result of which the number of spermatozoa was increased and the whole process of spermatogenesis was affected. The biologic action of jochimbin on the spermatogenesis of a rat was similar to that of the preparation TB-68, examined by us.