Serial study of C-reactive protein during infection in leukaemia

Serum C-reactive protein was studied serially by a 1-hour laser nephelometric assay in 25 patients with leukaemia who developed 34 episodes of infection. The serum level rose above, or by, 100mg/l in 29 of the episodes. Serial measurement of this acute-phase reactant was of value in detecting infection in the neutropenic patient and in monitoring the response to antibiotic therapy.