Multiple intracranial aneurysms associated with moyamoya disease. Case report

Area of Science:

• Neurology
• Neurosurgery
• Vascular Neurology

Background:

• Moyamoya disease is a rare, progressive cerebrovascular disorder characterized by stenosis of the terminal internal carotid arteries and development of collateral circulation.
• Intracranial aneurysms are abnormal bulges in the walls of blood vessels within the brain, posing a significant risk of rupture and hemorrhage.
• The association between moyamoya disease and intracranial aneurysms is recognized but requires further elucidation regarding specific patterns and locations.

Observation:

• This report details a specific case of multiple intracranial aneurysms co-occurring with unilateral moyamoya vessels.
• A comprehensive literature review was conducted, analyzing patient demographics (age, sex), presenting symptoms, aneurysm locations, and surgical treatment indications in similar reported cases.

Findings:

• Aneurysms associated with moyamoya disease demonstrate a frequent predilection for the vertebrobasilar arterial system.
• Analysis of similar cases suggests specific demographic and clinical profiles may be associated with this comorbidity.

Implications:

• Understanding the common locations of aneurysms in moyamoya disease can enhance diagnostic accuracy and inform targeted screening protocols.
• This knowledge aids neurosurgeons and neurologists in risk stratification and surgical planning for patients with moyamoya disease and associated aneurysms.
• Further research into the underlying pathophysiology may reveal shared mechanisms contributing to both moyamoya disease and aneurysm formation.