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Updated: Jun 10, 2026
14:58
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Embolization of Ruptured Cerebral Aneurysms with GDC in Acute Stage
Summary
Guglielmi detachable coils (GDCs) effectively treated 21 ruptured cerebral aneurysms in the acute stage. While most cases showed good occlusion, complications like reruptures occurred, necessitating careful assessment.
Area of Science:
- Neurosurgery
- Interventional Neuroradiology
- Vascular Neurology
Background:
- Ruptured cerebral aneurysms pose a significant risk of rebleeding and poor outcomes.
- Endovascular coiling has emerged as a primary treatment modality for acute cerebral aneurysms.
Purpose of the Study:
- To evaluate the efficacy and safety of Guglielmi detachable coils (GDCs) for treating ruptured cerebral aneurysms in the acute stage.
- To assess the outcomes and complication rates associated with GDC embolization in this patient cohort.
Main Methods:
- Retrospective analysis of 21 patients with ruptured cerebral aneurysms treated with GDCs.
- Patients were categorized by Hunt and Hess grades (1-4).
- GDC embolization was performed at varying intervals post-hemorrhage (within 24 hours, 2-3 days, 5-19 days).
Main Results:
- Successful intra-aneurysmal occlusion was achieved in varying degrees across the cohort.
- Occlusion rates were 100% in 7 aneurysms, >75% in 9, and <75% in 6.
- Complications included coil deposits (2), embolism (1), and reruptures (4).
Conclusions:
- Guglielmi detachable coils are a viable option for acute treatment of ruptured cerebral aneurysms.
- While effective for occlusion, careful monitoring is needed due to potential complications such as reruptures.
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