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Updated: Aug 11, 2026
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Pseudomembranous colitis with sparing of transplanted colon
The Medical Journal of Australia
|January 24, 1981
Summary
Pseudomembranous colitis (PMC) is linked to Clostridium difficile toxins. A unique case showed PMC only in the normally positioned colon, not the interposed segment, supporting the local toxin theory.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Infectious Diseases
Background:
- Pseudomembranous colitis (PMC) is strongly associated with Clostridium difficile toxins.
- Colon interposition is a surgical procedure for esophageal reconstruction.
Observation:
- A patient who underwent colon interposition for benign esophageal stricture developed pseudomembranous colitis.
- The colitis presented with florid features but was strictly confined to the normally sited colon.
Findings:
- The interposed colonic segment did not exhibit any pseudomembranous colitis changes.
- This is a unique case report with no similar findings documented in existing literature.
Implications:
- The findings support the hypothesis that PMC is caused by toxins from local fecal bacteria.
- Excluding the colon from the fecal stream, as in this surgical case, may prevent PMC occurrence.
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