[Central and renal hemodynamic indices under physical load in hypertension]

The article shows the results of studying the functional condition of the cardiovascular system in hypertensive disease. Under physical load healthy individuals demonstrated an increase in arterial pressure, rate of cardiac contractions, cardiac and stroke output, arteriovenous difference in oxygen, and diminution in the circulation volume, total peripheral resistance, renal blood flow and renal fraction of the minute blood volume. In patients with hypertensive disease there was a tendency to a lesser decrease in the cardiac output under load, the difference with the indices of healthy individuals increased with each stage of the disease. In hypertensive disease of stage IIB there were significantly smaller cardiac output, diminution of stroke volume under load, and a sharper rise than in the control group of arteriovenous difference in oxygen. The diminution of renal blood flow in response to the load was more marked in hypertensive disease.