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[Correlation analysis of coagulogram indices in stroke]
Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
|January 1, 1981
Summary
Analyzing blood clotting tests in stroke patients revealed key indicators for monitoring therapy. Plasma heparin tolerance, recalcification time, fibrinogen, fibrinolytic activity, and thrombotest are crucial for effective stroke treatment.
Area of Science:
- Medical research
- Hematology
- Neurology
Background:
- Stroke, a leading cause of disability, requires precise management of blood coagulation.
- Understanding hemocoagulation status is vital for effective anticoagulant and hemostatic therapy in stroke patients.
Purpose of the Study:
- To analyze correlations within expanded coagulograms of ischemic cerebral stroke and cerebral hemorrhage patients.
- To identify reliable hemocoagulation tests for monitoring stroke therapy across different age groups.
Main Methods:
- Statistical analysis of coagulograms from 850 ischemic stroke and 146 cerebral hemorrhage patients.
- Correlation analysis of coagulation parameters stratified by age groups (under 45, 45-59, 60+).
- Utilized a "Minsk-32" computer for data processing.
Main Results:
- Plasma tolerance of heparin, plasma recalcification time, fibrinogen, fibrinolytic activity, and thrombotest were identified as the most reliable indicators.
- Correlations between coagulogram parameters varied significantly based on stroke type and patient age.
- Age-dependent variations in coagulation parameter correlations were observed.
Conclusions:
- Specific hemocoagulation tests are essential for evaluating and managing stroke.
- Individualized therapy for stroke patients should consider age-specific variations in coagulation parameters.
- The findings support tailored therapeutic strategies in stroke management based on detailed coagulation profiles.