Mitral regurgitation and characteristic changes in impedance cardiogram
British Heart Journal
|May 1, 1981
Summary
Mitral regurgitation may cause unique impedance cardiography waveform changes. New indices derived from impedance cardiograms (delta Z and dZ/dt) can help identify patients with this condition.
Area of Science:
- Cardiology
- Biomedical Engineering
- Diagnostic Imaging
Background:
- Impedance cardiography (ICG) measures cardiac electrical activity.
- Typical ICG waveform abnormalities in mitral regurgitation are not well-defined.
- Distinguishing mitral regurgitation from other cardiac conditions using ICG requires further investigation.
Purpose of the Study:
- To investigate characteristic abnormalities in the impedance cardiographic waveform of patients with mitral regurgitation.
- To develop and validate indices from ICG tracings for identifying mitral regurgitation.
- To compare ICG findings in patients with mitral regurgitation against a normal control group.
Main Methods:
- Retrospective review of impedance cardiograms from patients who underwent cardiac catheterization.
- Selection of two groups: 22 with normal hearts and 36 with isolated mitral regurgitation.
- Calculation of delta Z index (C + X - V) and dZ/dt index (C' + X' - V') from ICG tracings.
Main Results:
- The mean delta Z index was significantly lower in the mitral regurgitation group (0.96 ohms) compared to the normal group (1.64 ohms).
- The mean dZ/dt index was also significantly lower in the mitral regurgitation group (0.48 ohms/s) versus the normal group (1.32 ohms/s).
- Despite some overlap, the calculated indices demonstrated statistically significant separation between the two groups.
Conclusions:
- Mitral regurgitation is associated with characteristic abnormalities in the impedance cardiographic waveform.
- The developed delta Z and dZ/dt indices may serve as useful tools for identifying patients with mitral regurgitation.
- ICG offers a potential non-invasive method for aiding in the diagnosis of mitral regurgitation.
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