Massive ovarian oedema. Case report

A case is described of massive ovarian oedema with secondary amenorrhoea and evidence of masculinization in a young girl. Pre-operative testosterone levels in peripheral plasma were markedly raised, but returned to normal immediately following wedge resection of both ovaries. Microscopic examination revealed lutein cells in the right ovary which were predominantly located within and around atretric follicles and Stein-Leventhal-like features in the left ovary. Irregular ovulatory cycles started four weeks after surgery.