Visual and auditory evoked potentials in a case of Marchiafava Bignami Disease

Brainstem auditory evoked potentials and visual evoked potentials to both flash and pattern reversal stimulation were recorded in a case of clinically diagnosed Marchiafava Bignami Disease (M.B.D.) A CT scan revealed dilation of the supratentorial ventricular system and fairly extensive cortical atrophy. The brainstem potentials showed a non-specific abnormality of the N4 component, (in the region of the caudal pons) and were inconclusive. The visual evoked potentials to flash stimulation were delayed while pattern reversal responses were within normal limits.