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Related Experiment Videos

Home peritoneal dialysis during infancy

W B Lorentz, R W Hamilton, B Disher

    Clinical Nephrology
    |April 1, 1981
    PubMed
    Summary
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    Home peritoneal dialysis (PD) is a viable option for infants with chronic renal failure, enabling them to await transplantation. While growth failure was observed, PD was generally well-tolerated in these young patients.

    Area of Science:

    • Pediatric Nephrology
    • Renal Replacement Therapy
    • Chronic Kidney Disease Management

    Background:

    • Infantile chronic renal failure necessitates renal replacement therapy.
    • Home peritoneal dialysis (PD) offers a treatment modality for infants awaiting transplantation.
    • Early initiation of PD in infants under 10 kg is feasible.

    Observation:

    • Two infants with end-stage renal disease initiated chronic home PD before one year of age.
    • Dialysis was performed for 10 and 13 months, respectively, pending cadaveric kidney transplantation.
    • Infants were monitored for growth, dialysis tolerance, and complications such as peritonitis.

    Findings:

    • Both infants experienced significant growth failure during home PD treatment.
    • One infant had three episodes of peritonitis, while the other remained peritonitis-free for 10 months.

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  • Chronic home PD was considered well-tolerated overall in both cases.

    • Implications:

    • Home PD can support infants with chronic renal failure, bridging the gap to transplantation.
    • Growth failure is a notable concern requiring careful management in infants undergoing chronic PD.
    • Further research is needed to optimize growth and minimize complications in pediatric PD patients.