Increased focal uptake of Tc-99m-IDA hepatobiliary agent by a liver metastasis

A patient with fever and right upper quadrant abdominal pain referred for a hepatobiliary scan. TC-99m-PIPIDA scanning revealed a hypervascular hepatic focus that persisted as a "hot spot" in delayed views. Ga-67-citrate scanning revealed increased uptake in the same hepatic focus. The patient suddenly died. Postmortem examination revealed that this abnormal site represented a necrotic tumor histologically compatible with metastatic breast carcinoma.