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Related Experiment Videos

Hemoccult screening in selected patients

P B Daron, L I Goldman

    Southern Medical Journal
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Fecal occult blood testing in asymptomatic patients undergoing hernia repair detected colonic disease in 7% of cases. A meat-free diet significantly reduced false positives, improving test accuracy for gastrointestinal screening.

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    Area of Science:

    • Gastroenterology
    • Colorectal Cancer Screening
    • Surgical Patient Evaluation

    Background:

    • Assessing the utility of fecal occult blood testing (FOBT) in asymptomatic patients undergoing elective hernia repair.
    • Evaluating the prevalence of undiagnosed colonic disease in this patient population.
    • Investigating factors influencing the accuracy of FOBT.

    Observation:

    • One hundred asymptomatic patients scheduled for hernia repair were screened for occult blood in stool.
    • Twenty-six percent of patients had one or more positive stool specimens.
    • A significant false-positive rate of 33% was observed in initial testing.

    Findings:

    • Colonic disease was diagnosed in seven patients (7%) with positive FOBT results.
    • Diagnoses included one adenocarcinoma (Dukes' stage A), three adenomatous polyps, and remaining colonic diverticula.

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  • Implementing a meat-free diet prior to stool collection markedly reduced the false-positive rate.

    • Implications:

    • FOBT may identify occult colonic disease in unexpected patient groups like those undergoing hernia repair.
    • Dietary modifications can enhance the specificity of FOBT, reducing unnecessary follow-up procedures.
    • This screening approach appears cost-effective and feasible for improving early detection of colorectal pathology.