Jove
Visualize
Contact Us

Related Experiment Videos

Hepatotoxicity following enflurane anesthesia

L B White, G O DeTarnowsky, J A Mir

    Digestive Diseases and Sciences
    |May 1, 1981
    PubMed
    Summary

    Severe liver injury occurred in a patient after enflurane anesthesia. This case highlights potential risks associated with this anesthetic agent.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Characterisation of the Medipix3 detector for 60 and 80keV electrons.

    Ultramicroscopy·2017
    Same author

    An assessment of racial differences in the upper limits of normal ALT levels in children and the effect of obesity on elevated values.

    Pediatric obesity·2016
    Same author

    Characterizing hepatitis B stigma in Chinese immigrants.

    Journal of viral hepatitis·2012
    Same author

    Hepatocyte proliferation and hepatitis C virus kinetics during treatment.

    Clinical pharmacology and therapeutics·2011
    Same author

    Very early prediction of response to HCV treatment with PEG-IFN-alfa-2a and ribavirin in HIV/HCV-coinfected patients.

    Journal of viral hepatitis·2010
    Same author

    Cholesterol and basal metabolism.

    The American journal of medical technology·2010
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Anesthesiology
    • Hepatology
    • Toxicology

    Background:

    • Anesthesia is crucial for surgical procedures.
    • Volatile anesthetics like enflurane are commonly used.
    • Understanding anesthetic risks is vital for patient safety.

    Observation:

    • A patient exhibited signs of liver damage.
    • Clinical, biochemical, and histologic data confirmed hepatic injury.
    • The injury was temporally associated with enflurane anesthesia.

    Findings:

    • Enflurane anesthesia was linked to severe hepatic injury.
    • The patient's liver damage was significant and evident across multiple measures.
    • This suggests a potential hepatotoxic effect of enflurane.

    Implications:

    • This case underscores the importance of monitoring liver function post-anesthesia.
    • It may prompt further investigation into enflurane's hepatotoxicity.
    • Clinicians should consider alternative anesthetic agents in at-risk patients.

    Related Experiment Videos