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Auditory brain stem responses in thyroid dysfunction

M Z Himelfarb, T Lakretz, S Gold

    The Journal of Laryngology and Otology
    |July 1, 1981
    PubMed
    Summary
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    Thyroid dysfunction alters auditory brainstem response (ABR) patterns, particularly the brainstem conduction time (BSCT). ABR assessment may help evaluate thyroid status.

    Area of Science:

    • Neuroscience
    • Endocrinology
    • Audiology

    Background:

    • Thyroid hormones significantly influence neurological function.
    • Auditory brainstem response (ABR) reflects the integrity of the auditory pathway.
    • Changes in thyroid status can impact central nervous system function.

    Purpose of the Study:

    • To investigate the characteristic alterations in ABR patterns associated with thyroid gland dysfunction (hyper- and hypothyroidism).
    • To explore the relationship between ABR parameters and serum thyroxine (T4) levels.
    • To assess the dynamic changes in ABR during the development and recovery from myxedema.

    Main Methods:

    • Auditory brainstem response (ABR) testing was performed on individuals with thyroid dysfunction.
    • Brainstem conduction time (BSCT) was analyzed as a key ABR parameter.

    Related Experiment Videos

  • Correlation analysis was conducted between BSCT values and serum T4 levels.
  • Longitudinal ABR recordings were obtained during myxedema development and euthyroid state recovery.

    • Main Results:

    • A distinct ABR pattern was observed in both hyperthyroid and hypothyroid states.
    • BSCT showed a significant correlation with serum T4 levels.
    • Dynamic shifts in ABR patterns were documented throughout the progression and resolution of myxedema.

    Conclusions:

    • ABR testing reveals characteristic changes related to thyroid gland function.
    • BSCT is a sensitive indicator that correlates with thyroid hormone levels.
    • ABR examination shows potential as a supplementary tool for assessing thyroid status.