[Metal content of nucleic acids in experimental leukosis]

An instrumental neutron-activated analysis was carried out to study metal content in nucleic acids preparations of the rat liver and tumour subjected to Shvets erythromyelosis. It was determined that the DNA and RNA preparations contain iron, zinc, silver, cobalt and scandium. According to the level of concentration of revealed metals are arranged in the row in the following order: iron less than zinc less than silver less than cobalt less than scandium. The iron and zinc contents in RNA is almost twice as high as those in DNA. The content shifts in some of the revealed metals (the iron and scandium contents in DNA preparation of the liver, zinc and iron contents in the DNA preparation of the tumour and zinc content in the RNA preparations of the liver) in the process of the development of leukosis are characterized by a tendency to their increase.