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[Effect of cryoprotectors on stability of lysosomes under cooling]
Ukrainskii Biokhimicheskii Zhurnal (1978)
|September 1, 1980
Abstract:
The efficiency of cryoprotectors-polyethylene oxide 400, glycerol, oxyethylated glycerol, dimethyl sulphoxide was studied relative to stabilization isolated lysosomes under different regimes of freezing-thawing. It is established that a decrease in the amount of lysosome hydrolases (RNase, DNase, catepsin D, phosphatase) released to the environment is the most significant in the presence of the mentioned substances uncer slow freezing-thawing.