[Dynamics of the changes in the acid-base state in acquired heart defects]

One hundred thirty nine patients with acquired valvular defects were examined, 72 of them followed up dynamically. The dynamic changes in the indices of ABS were studied as well as the pressure of arterial blood gases, some electrolytes in blood serum, the basic indices of external respiration, diffusion capacity of lungs for CO, alveolar-arterial gradients for O2, functional and true shunts, etc. The results showed that the disorders found in ABS were, to a great extent, reversible after complex treatment carried out. Most intensive was the dynamics of recovery at stage IIB and the poorest stage IIA of cardiac insufficiency. The changes in respiratory function play a leading role in the genesis of ABS disorders. The diuretics and electrolyte deviations are of secondary importance. The dynamic investigations on ABS in parallel with some indices of respiratory function provide an early and accurate assessment of the functional state of the respiration system in acquired valvular defects, a more complete estimation of the results from the treatment, evolution and prognosis, revealing some of the complicated mechanisms of those disorders.