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Updated: Aug 11, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 23, 2014
Abstract:
Disseminated cutaneous lupus erythematosus is a recently defined variant of lupus erythematosus. It presents as migratory areas of annular erythema, but lacks the atrophy, scarring, and follicular plugging associated with discoid lupus erythematosus. The clinical manifestations of this disease fall somewhere in between those associated with classic discoid lupus erythematosus and those associated with systemic lupus erythematosus. A case of disseminated cutaneous lupus erythematosus occurring in a 91-year-old woman is presented. This patient developed areas of subepidermal cleavage resulting in clinically apparent flat vesiculation with subsequent crusting and erosion. Lupus erythematosus must be considered in the differential diagnosis of migratory annular erythema with or without vesiculation.
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