Jove
Visualize
Contact Us

Related Experiment Videos

Collagen formation by periretinal cellular membranes

H Laqua

    Developments in Ophthalmology
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Retinal pigment epithelial and glial cells can produce collagen after retinal detachment. This collagen is similar to vitreous collagen, found in newly formed membranes within the eye.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An effective sub-quadratic scaling atomic-orbital reformulation of the scaled opposite-spin RI-CC2 ground-state model using Cholesky-decomposed densities and an attenuated Coulomb metric.

    The Journal of chemical physics·2022
    Same author

    First results from the implementation of the ITER diagnostic residual gas analyzer prototype at Wendelstein 7-X.

    The Review of scientific instruments·2019
    Same author

    Generation of organized Lacrimal gland cell spheroids by simulated microgravity.

    Journal of stem cells & regenerative medicine·2014
    Same author

    Amniotic membrane as a matrix for lacrimal gland tissue engineering.

    Journal of stem cells & regenerative medicine·2014
    Same author

    Cultivation of lacrimal gland acinar cells in a microgravity environment.

    The British journal of ophthalmology·2009
    Same author

    Diagnostic developments for quasicontinuous operation of the Wendelstein 7-X stellarator.

    The Review of scientific instruments·2008
    Same journal

    Erratum.

    Developments in ophthalmology·2021
    Same journal

    Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography.

    Developments in ophthalmology·2021
    Same journal

    Integrated Intraoperative Optical Coherence Tomography for Pediatric Lamellar Corneal Transplant Surgery.

    Developments in ophthalmology·2021
    Same journal

    The Use of Optical Coherence Tomography as an Intraoperative Adjunct of Oculoplastic Surgery.

    Developments in ophthalmology·2021
    Same journal

    Integrated Intraoperative Optical Coherence Tomography in Strabismus Surgery.

    Developments in ophthalmology·2021
    Same journal

    Use of Integrated Intraoperative Ocular Coherence Tomography in Pediatric Cataract Surgery: Thinking outside the Box.

    Developments in ophthalmology·2021
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Ophthalmology
    • Cell Biology
    • Biochemistry

    Background:

    • Retinal detachment can lead to the formation of cellular membranes.
    • The subretinal space typically lacks collagen.

    Purpose of the Study:

    • To investigate collagen production by retinal cells in experimental retinal detachment.
    • To characterize the type of collagen formed in subretinal membranes.

    Main Methods:

    • Induction of experimental retinal detachment in eyes.
    • Microscopic examination of cellular membranes in the subretinal space.
    • Biochemical analysis of collagen within these membranes.

    Main Results:

    • Pigment epithelial cells and glial cells formed membranes on available surfaces.

    Related Experiment Videos

  • Collagen was detected in the intercellular spaces of these membranes.
  • The identified collagen was indistinguishable from vitreous collagen.

    • Conclusions:

    • Retinal pigment epithelial cells and glial cells are capable of synthesizing collagen.
    • The newly produced collagen resembles native vitreous collagen.