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[Ménétrier's disease simulating pangastritis]

A Fröhlich, G Bálint, A Molnár

    Morphologiai Es Igazsagugyi Orvosi Szemle
    |July 1, 1981
    PubMed
    Summary

    A rare case of giant hypertrophic gastritis mimicked stomach cancer in a 38-year-old male. Surgical removal revealed inflammatory changes, not a tumor, highlighting diagnostic challenges.

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    Area of Science:

    • Gastroenterology
    • Pathology

    Background:

    • Giant hypertrophic gastritis (GHG) is a rare condition characterized by significant thickening of the gastric mucosa.
    • GHG can present with symptoms and imaging findings that mimic gastric malignancy, posing diagnostic challenges.

    Observation:

    • A 38-year-old male presented with clinical and radiographic findings suggestive of a gastric tumor.
    • The patient underwent surgical resection of the suspected gastric tumor.

    Findings:

    • Histopathological examination revealed diffuse inflammatory changes consistent with pangastritis, including submucosal micro-abscesses.
    • The resected specimen showed no evidence of malignancy, confirming a benign inflammatory process.

    Implications:

    • This case underscores the importance of considering GHG in the differential diagnosis of gastric masses.
    • Accurate diagnosis requires a combination of clinical, radiological, and histological evaluation to avoid unnecessary radical surgery.
    • Understanding the pathogenesis and diagnostic nuances of GHG is crucial for appropriate patient management.

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