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[Capillary hypoperfusion in diabetes mellitus: a comparative microscopic study on its pathogenesis and temporal
Abstract:
In animal experimental alloxan diabetes changes the distribution of microcirculation with reduction of the nutritive capillary perfusion and simultaneous formation of hyperperfused functional microshunts. The nutritive capillary hypoperfusion is due to an increased precapillary vasoconstriction and a changed rheological behaviour of the blood with increase of the cohesive forces between the erythrocytes (aggregation of erythrocytes) and the intravascular cellular swellings.