[Structural variants, hyperplastic changes and tumors of the major duodenal papilla (based on surgical material from patients with chronic recurrent pancreatitis)]

Morphological studies of 15 polyps of the major duodenal papilla (MDP), 50 amputated MDPs and 5 ectomized MDPs from patients with chronic relapsing pancreatitis were carried out. Three groups of changes were detected: (1) variants of the structure: separate confluence of the common bile and major pancreatic ducts into the duodenum, additional pancreatic ducts, dystopia of the pancreatic gland tissue; (2) hyperplastic changes: papillomatosis of the MDP opening, intrapapillar adenomatous polyps, adenomyosis of MDP wall; (3) tumors: adenoma and carcinomas. No relationship between hyperplasias and calculi and inflammation of bile ducts was confirmed. Some kinds of MDP pathology were found to depend on variants of its structure. Papillomatosis of MDP was shown to be capable of malignancy.