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Brain involvement in hepatosplenic Schistosomiasis mansoni
Brain : a Journal of Neurology
|September 1, 1981
Summary
Schistosoma mansoni eggs can invade the brain in patients with hepatosplenic schistosomiasis. This study found parasite eggs in 26% of brains examined, suggesting frequent neurological involvement in this parasitic disease.
Area of Science:
- Neurology
- Infectious Diseases
- Parasitology
Background:
- Hepatosplenic schistosomiasis mansoni is a chronic parasitic disease.
- Neurological complications are not well-characterized in this condition.
Purpose of the Study:
- To investigate the prevalence and characteristics of brain involvement in patients with hepatosplenic schistosomiasis mansoni.
Main Methods:
- Autopsy examination of brains from 46 patients with hepatosplenic schistosomiasis mansoni.
- Histopathological analysis to detect Schistosoma mansoni eggs.
Main Results:
- Schistosoma mansoni eggs were identified in the brains of 12 out of 46 patients (26%).
- The location of parasite eggs, host brain reaction, and clinical manifestations were analyzed.
Conclusions:
- Brain involvement is a common finding in hepatosplenic schistosomiasis mansoni.
- The study discusses potential routes of parasite egg migration to the central nervous system.